From Beaumont
Take I-10 West to
59 South
Exit Fannin and veer left
Cross Dryden
Right into St. Luke's Medical Tower Garage

From Katy
Take I-10 East to
45 South to
59 South
Exit Fannin and veer left
Cross Dryden
Right into St. Luke's Medical Tower Garage

From Sugar Land
Take 59 North
Exit Kirby and turn right
Left onto Holcombe
Left onto Fannin
Left into St. Luke's Medical Tower Garage

From Clear Lake/Hobby Airport
Take 45 North to
59 South
Exit Fannin and veer left
Cross Dryden
Right into St. Luke's Medical Tower Garage

From The Woodlands/
Bush Intercontinental Airport
Take 45 South to
59 South
Exit Fannin and veer left
Cross Dryden
Right into St. Luke's Medical Tower Garage

From Cy-Fair Area
Take 290 East to
59 North
Exit Kirby and turn right
Left onto Holcombe
Left onto Fannin
Left into St. Luke's Medical Tower Garage

From Kingwood
Take 59 South
Exit Fannin and veer left
Cross Dryden
Right into St. Luke's Medical Tower Garage